This variant browser currently shows chromosome locations, alleles, VEP functional annotations,
and allele frequencies for 170,041,149 variants observed in 14,559 individuals
sequenced in NHLBI's TOPMed program.
The information is shared by TOPMed Phase 1 studies
and is available for users that agree to the terms.
The sequencing analysis pipeline consists of two major processes:
- Harmonization of data from the BAM files provided by the sequencing centers and
- Joint variant discovery and genotype calling across studies.
The alignment pipeline is available at github.com/statgen/gotcloud
and the variant calling pipeline is available at github.com/statgen/topmed_freeze3_calling
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